Brain Tumor Funders' Collaborative

Brain Tumour Foundation of Canada partners with the Brain Tumor Funders' Collaborative to extend the impact of research dollars.

Five North American funding organizations make up the Brain Tumor Funders' Collaborative.  The organization includes Brain Tumour Foundation of Canada along with five other non-profit, philanthropic and advocacy organizations from the United States. By working together we can accelerate progress in brain tumor research. The groups have worked together to fund two previous initiatives (details below) and are now exploring a third joint project. When this is finalized, the projects details, and any applicable calls for applications will be posted here.

Read the May 2016 report from the Brain Tumor Funder's Collaborative.
Long-term survival in glioblastoma - a project of the Brain Tumor Funders` Collaborative: Read the latest update here.

The members of the Brain Tumour Funders' Collaborative are: 

  • American Brain Tumor Association
  • Brain Tumour Foundation of Canada
  • Children’s Brain Tumour Foundation
  • James S. McDonnell Foundation
  • Sontag Foundation

The eleven projects granted funding in 2010 were:

In January, 2010, the Brain Tumor Funders’ Collaborative (BTFC) announced the award of 11 one-year feasibility grants of $100,000 each to teams of researchers and clinicians developing the types of tools needed to translate scientific discoveries into effective new treatments for brain cancer patients. This is BTFC’s second joint initiative for brain tumor research and is intended to accelerate the testing of different kinds of brain tumor response markers – reliable, easily monitored biological signals that can reveal if and how a tumor is responding to therapies.

Urinary Biomarkers for Non-invasive Assessment of Therapeutic Efficacy in Glioma
Children's Hospital Boston
Investigator: Edward R. Smith

Development of Protein Arrays for the Detection of Biomarkers in the CSF of Brain Tumor Patients
Emory University School of Medicine
Investigator: Erwin G. Van Meir

Amide Proton Transfer MR Imaging to Assess Tumor Response in Patients with Gliomas
Johns Hopkins University
Investigator: Jaishri O. Blakeley

Circulating Tumor DNA as a Dynamic Biomarker in Malignant Gliomas
Johns Hopkins University
Investigator: Luis A. Diaz

Non-invasive Assessment of Glutamate in Glioblastoma Multiforme: Effect of Treatment
Johns Hopkins University
Investigator: Alena Hoska

Exosome Analysis: A Non-Invasive Approach to Monitor Treatment Responses in Glioma Patients
Massachusetts General Hospital
Investigator: Bob S. Carter

Molecular Determinants of [18F]FACBC-PET Imaging in Brain Tumors
Memorial Sloan-Kettering Cancer Center
Investigator: Andrew B. Lassman

Combining Genomics with Physiologic Imaging Biomarkers to Predict and Follow Treatment Response in Glioma
University of California (David Geffen School of Medicine at UCLA)
Investigator: Whitney B. Pope

A combined molecular and clinical predictor of progression vs. pseudoprogression in newly diagnosed GBM

University of Texas MD Anderson Cancer Center
Investigator: Kenneth D. Aldape

Patient-specific Metrics of Treatment Response

University of Washington
Investigator: Kristin R. Swanson

Monitoring Response to Therapy in Malignant Glioma Patients Using Blood-Based Epigenomic and Proteomic Biomarkers
Vanderbilt University Medical Center
Investigator: Kyle D. Weaver

In 2006, three, $2 million, multi-year grants projects were selected for funding. They met the goal to promote collaborative, innovative and novel research approaches for pre-clinical systems to accelerate more effective outcomes for patients with gliomas.

Tumor Stem Cell-Based Drug Discovery for Adult and Pediatric Glioma
Kennedy- Krieger Institute, Johns Hopkins University, Baltimore, Maryland
Investigator: Dr. John Laterra

Molecularly Guided Clinical Trials for Glioma
David Geffen School of Medicine at UCLA
Ivestigator: Dr. Paul Mischel

Identifying and Overcoming Resistance Mechanisms in Glioblastomas: A Joint EORTC-RTOG Effort
American College of Radiology/Radiation Therapy Oncology Group
Investigator: Dr. Minesh Mehta

Learn more about the projects and the organization at


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