2012 Researcher Karen Goddard

Feasibility Study: Cerebrovascular disease and Late Effects in Survivors of Craniopharyngioma

Karen Goddard
BC Cancer Research Agency: Vancouver, British Columbia
$24,820.00

What does the title mean?

The research will provide a model for screening and intervention of cerebrovascular disease in brain tumour survivors, a frequent long-term complication associated with the treatment of non-malignant craniopharyngiomas. [no photo]


Project Summary:

Survivors of both pediatric and young adult craniopharyngiomas are at risk for significant late effects. Although these tumors are benign, they generally require both surgery and high dose radiation therapy (RT) for long term control. Documented late health problems include hypopituitarism, cognitive disabilities, visual deficits and hypothalamic-obesity.

More recently, cerebrovascular disease (CVD) has also been found to be a frequent long-term complication, and this has not yet been studied in any significant number of patients. We do not know the frequency or types of CVD, the difference in onset and type between survivors of childhood versus young adult tumors, the amenability of these malformations to interventional therapy, the clinical correlation with TIAs and stroke-like symptoms, and the frequency of conditions such as obesity and hypertension which may increase the risk of CVD in survivors. We propose a comprehensive study to answer these questions involving clinical assessment and MR angiography.

We are conducting a feasibility study on an initial 20 survivors prior to a study involving the entire cohort. This research will provide a model for screening and intervention of CVD in brain tumour survivors. Our goal is to reduce late morbidity and mortality in this population.
 

Share This

Featured Story

Childhood Brain Tumour Signs & Symptoms

Earlier this year, you gave us your feedback in a survey on brain tumour signs and symptoms. One of the things we did with that survey was to compile a list of the most common signs & symptoms for children. Now, as part of Childhood Cancer Awareness Month, we are sharing compelling quotes from that survey and urging you to share them with this link to see the symptoms: www.braintumour.ca/symptoms. Thank you!

Learn more

Spotlight

Anthony's Story is Our Story

I would like to take the opportunity to share "our" story. It’s actually my best friend Anthony's story, but I use the term "our"...

Learn more

Kate's Mum's Story

"May 2006 is a month I will never forget. That was the moment that everything became before the cancer, and after the cancer. It was a...

Learn more

Upcoming Events

  • 15/Oct/2018: Virtual Support Group for Caregivers: Virtual Support Group for Caregivers... Learn more >
  • 15/Oct/2018: Guelph Support Group: Meets at Hospice Wellington, Community Program Room, 795 Scottsdale Avenue,... Learn more >
  • 15/Oct/2018: Mississauga Support Group: Meets at Westminster United Church, 4094 Tomken Rd., Mississauga, ON... Learn more >
  • 15/Oct/2018: Edmonton Support Group: Meets at Wellspring Edmonton, 11306 65 Ave NW, Edmonton, AB ... Learn more >
View All Events >
Thank you to the donors whose contributions make this website and all programs, services and research possible.

Copyright © 2018 Brain Tumour Foundation of Canada. Charitable Registration #BN118816339RR0001