2013 Researcher Dr. Mark Ruschin

Comparison of healthy tissue sparing using different radiation delivery devices for focal irradiation of multiple brain metastases

Dr. Mark Ruschin brain tumour researcherDr. Mark Ruschin
Sunnybrook Odette Cancer Centre, Toronto, ON
Award: $18,500

Dr. Ruschin's project is funded in memory of and through the generosity of Donald J.T.A. de Jong



Project Summary:

Brain metastases occur in 20-40% of people with cancer, and will lead to over 7,000 diagnosed cases in 2013. For these individuals, quality of life is of the utmost importance. The traditional approach to managing patients with brain metastases is to perform whole brain radiation, in which the entire brain receives a uniform dose of radiation in order to stop the diagnosed brain metastases from growing, and to prevent new brain metastases from forming.

Whole brain radiotherapy, however, adversely affects cognitive function and limits further treatment should additional brain metastases develop. Focal radiation targets individual brain metastases and spares the healthy brain, which maintains better cognitive function and provides excellent tumor control. Various radiation therapy technologies are capable of focal radiation.

One new device has recently become Health Canada approved and exhibits improved characteristics over predecessors such as faster radiation delivery, and lower leakage radiation. We hypothesize that this new device can be used to treat patients with multiple brain metastases in a focal/ablative fashion, thus better preserving patients’ cognitive function and improving quality of life. The focus of this work is technique development and a comparison of radiation dose distributions to the current standard.

<back to 2013 Research Grant Awardees

Share This

Featured Story

Kate's Mum's Story

"May 2006 is a month I will never forget. That was the moment that everything became before the cancer, and after the cancer. It was a mark in time that would forever change my family"... Read more about Kate's Mum's story from her diagnosis of glioblastoma in 2006 and how Mum has beaten the odds to still be here today.

Learn more

Spotlight

Roy and the Gamma Knife – A Happy Tale

I had headaches, almost daily, for 10 years or more. It was a rare day if I did not have a headache. I used to joke that I should own...

Learn more

Courtney’s Story of Stability

Stability. It’s a strange concept when you have what it known to be a progressive, life long illness. You hear the words, “Your tumour...

Learn more

Upcoming Events

  • 24/Jul/2018: Groupe de soutien virtuel: Un groupe de soutien virtuel pour personnes touchées par une tumeur... Learn more >
  • 25/Jul/2018: Toronto Support Group: Meets at Wellspring Westerkirk House at Sunnybrook, Toronto, ON... Learn more >
  • 29/Jul/2018: 11th Annual Black Diamond Car Show Presented by Thumbs Up: Black Diamond, AB... Learn more >
  • 02/Aug/2018: Ajax Support Group: Meets at St. Paul's United Church, 65 King's Crescent, Ajax, ON... Learn more >
View All Events >
Thank you to the donors whose contributions make this website and all programs, services and research possible.

Copyright © 2018 Brain Tumour Foundation of Canada. Charitable Registration #BN118816339RR0001