HOPE

Bevacizumab (Avastin®) Update – June 2013

New research about the brain tumour treatment Bevacizumab (Avastin®) was released at the recent American Society of Clinical Oncology (ASCO) 2013 Annual Meeting. Results were presented from two recent clinical trials focused on the treatment. Because Avastin is one of the few new treatments that have been offered to brain tumour patients in recent years, Brain Tumour Foundation of Canada was eagerly awaiting these results.

There were two separate clinical trials (AVAglio and RTOG 0825). Both examined the effectiveness of adding Avastin to the standard of care treatment for newly diagnosed glioblastoma multiforme (GBM) patients.

From the information presented at the meeting and from speaking to members of our Professional Advisory Group and representatives from the maker of the drug in Canada, Roche, we learned that Avastin appears unable, as a frontline treatment, to extend the lives of a statistically significant portion of GBM patients.

Since Avastin’s approval for treatment in Canada is for recurrent GBM, we know that many patients in Canada have had some positive experiences, but we hoped to see improved survival rates for all patients in these large and lengthy trials.

Another outcome from the research seems to be conflicting descriptions about the treatment’s ability to improve a patient’s quality of life. The two trials used different criteria to measure this and as a result offered different data on patients’ quality of life. More studies are needed among the many different individuals affected to understand this further.

In Canada, Avastin remains approved for patients with recurrent GBM – and is one of an all-too-limited tool box to treat brain tumours. At this point, it is unclear if Avastin’s status will change based on the results of these studies. If there is an application to the pan-Canadian Oncology Drug Review, Brain Tumour Foundation of Canada will be there to present the patient voice.

We will continue to track updates about this treatment and the impact of it, and any others, on the brain tumour community and we will continue to advocate for accessible treatment options for all Canadians diagnosed with a brain tumour.

Finally, we note the continued importance of research as we work towards the vision to find the cause of and a cure for brain tumours. We will continue to not only advocate on these issues but demand more research into this deadly disease and rally the community to raise funds to ensure a cure will be found.

We are here to help

There are many resources and programs available to anyone affected by a brain tumour. You can contact the toll free support and information line available Monday to Friday with any questions Monday through Friday, 8:30 am to 4:30 pm (EST):

1-800-265-5106

  • For informal, one-to-one support
  • To request a customized information package
  • To find out about support groups, agencies and resources in your community

You can also forward your questions to:


Janic Gorayeb
Health Information Specialist
jgorayeb@braintumour.ca
1-800-265-5106 or 519-642-7755 ext 233

- See more at: http://www.braintumour.ca/229/about-brain-tumours#sthash.jQLAG6XJ.dpuf

We are here to help

There are many resources and programs available to anyone affected by a brain tumour. You can contact the toll free support and information line available Monday to Friday with any questions Monday through Friday, 8:30 am to 4:30 pm (EST):

1-800-265-5106

  • For informal, one-to-one support
  • To request a customized information package
  • To find out about support groups, agencies and resources in your community

You can also forward your questions to:


Janic Gorayeb
Health Information Specialist
jgorayeb@braintumour.ca
1-800-265-5106 or 519-642-7755 ext 233

- See more at: http://www.braintumour.ca/229/about-brain-tumours#sthash.jQLAG6XJ.dpuf

We are here to help

There are many resources and programs available to anyone affected by a brain tumour. You can contact the toll free support and information line available Monday to Friday with any questions Monday through Friday, 8:30 am to 4:30 pm (EST):

1-800-265-5106

  • For informal, one-to-one support
  • To request a customized information package
  • To find out about support groups, agencies and resources in your community

You can also forward your questions to:


Janic Gorayeb
Health Information Specialist
jgorayeb@braintumour.ca
1-800-265-5106 or 519-642-7755 ext 233

- See more at: http://www.braintumour.ca/229/about-brain-tumours#sthash.jQLAG6XJ.dpuf=+=

We are here to help

There are many resources and programs available to anyone affected by a brain tumour. You can contact the toll free support and information line available Monday to Friday with any questions Monday through Friday, 8:30 am to 4:30 pm (EST):

1-800-265-5106

  • For informal, one-to-one support
  • To request a customized information package
  • To find out about support groups, agencies and resources in your community

You can also forward your questions to:


Janic Gorayeb
Health Information Specialist
jgorayeb@braintumour.ca
1-800-265-5106 or 519-642-7755 ext 233

- See more at: http://www.braintumour.ca/229/about-brain-tumours#sthash.jQLAG6XJ.dpuf

We are here to help

There are many resources and programs available to anyone affected by a brain tumour. You can contact the toll free support and information line available Monday to Friday with any questions Monday through Friday, 8:30 am to 4:30 pm (EST):

1-800-265-5106

- See more at: http://www.braintumour.ca/229/about-brain-tumours#sthash.jQLAG6XJ.dpuf

We are here to help:

We are here to help

There are many resources and programs available to anyone affected by a brain tumour. You can contact the toll free support and information line available Monday to Friday with any questions Monday through Friday, 8:30 am to 4:30 pm (EST):

1-800-265-5106

- See more at: http://www.braintumour.ca/229/about-brain-tumours#sthash.jQLAG6XJ.dpuf

There are many resources and services available to anyone affected by a brain tumour.  You can contact us toll free, Monday to Friday from 8:30 am to 4:30 pm for information and support: 1-800-265-5106.

Find the Information Sheet about Bevacizumab (Avastin®)

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