Primitive Neuroectodermal Tumours (PNET)

Overview


Tumour Group: Other Brain Tumours and Related Conditions
WHO Grade: Grade IV
Prevalence/Incidence:  
Typical Age Range:  

Contents
Description of Tumour
Symptoms
Treatment / Standard of Care
Prognosis
References

Description of Tumour


The pathology of primitive neuroectodermal tumours (PNET) is identical to medulloblastomas but PNETs occur primarily in the cerebrum (versus the cerebellum in the case of medulloblastoma). The cells of these rare tumours are generally not alike and they are fast growing. PNET cells are found throughout the brain and tend to seed (spread in the spinal fluid).

Types of PNET include:

  • Cerebral neuroblastoma (located in hemispheres)
  • Ependymoblastoma (arises from ventricles)
  • Pineoblastoma (occurs in area of pineal gland)

Symptoms


Limited information regarding the symptoms of PNET.

Treatment / Standard of Care


PNETs are treated with complete surgical removal, if possible, and are followed by radiation and chemotherapy.

Prognosis  


A prognosis is an estimate of the likely progress of a disease after a diagnosis, based on an average patient group. Since every person is different, please take time to talk with your health care team about how this information applies to you.

By clicking on 'Expand,' a statistic on the prognosis for primitive neuroectodermal tumours will be shown.

Expand for Prognosis Information

For brain tumour patients, a prognosis depends on several factors, which can include age and other health issues, the size of the tumour, its molecular profile, the type of tumour, how much can be removed, and its response to treatments such as chemotherapy and radiation therapy.

Limited information available for this type of tumour and/or related conditions.

References


Image credited to Paddy Mendez R. (Own work) [CC-BY-SA-3.0 (http://creativecommons.org/licenses/by-sa/3.0)], via Wikimedia Commons

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