Dr. Cavalli explains what the research means to her:<\/h3>\n
After integration of somatic copy number alterations and clinical features, we identified\u00a0twelve medulloblastoma subtypes\u00a0<\/strong>with clear clinical and molecular characteristics; two WNT, four SHH, three Group 3 and three Group 4 subtypes. These subtypes are important clinically since they present distinct clinical outcome and\/or distinct molecular characteristics at the copy number levels or pathway level for example.\u00a0Read the entire report (PDF)<\/a>\u00a0and read the\u00a0press release<\/a>\u00a0issued by SickKids.<\/p>\n This Brain Tumour Research Fellowship was generously established in 2013, in memory of Stephen Buttrum, the husband of Vice-Chair of the Board of Directors Marjory Buttrum.<\/p>\n \u201cWe chose to fund a Brain Tumour Research Fellowship because it was important to us that our gift would make a difference to the well-being of others. Steve was a generous man\u2026generous with his money, time and compassion for others, particularly children. He would be happy to know we are funding research to better understand and treat pediatric brain tumours.\u00a0\u00bb<\/p>\n – Marjory Buttrum, Brain Tumour Foundation of Canada\u00a0donor and board member<\/p><\/blockquote>\n <\/p>\n Florence Cavalli, Stephen Buttrum Brain Tumour Research Fellow. Project Title: Deciphering the transcriptional regulation underlying Medulloblastoma subgroups.<\/p>\n","protected":false},"featured_media":1179,"menu_order":0,"template":"","research_recipient_type":[283],"class_list":["post-4744","research_recipients","type-research_recipients","status-publish","has-post-thumbnail","hentry","research_recipient_type-fellowship-fr"],"acf":[],"yoast_head":"\n![\"Florence](\"https:\/\/braintumour.ca\/wp-content\/uploads\/2019\/10\/Florence-Cavalli-ButtrumFellow-e1570282712452-300x230.jpg\")
\u00ab\u00a0Being awarded the Stephen Buttrum Brain Tumour Research Fellowship represents a formidable opportunity to grow as a researcher and continue my research into a brain tumour type arising in children; medulloblastoma. I am passionate about my research, which focuses on increasing our understanding of the biology of medulloblastoma tumours to ultimately find better treatments.\u00a0I am driven by the idea that my efforts will contribute to reduce the devastating effects of this disease on young patients and their families.\u00a0\u00bb<\/strong><\/p>\nFrom the final report:<\/h3>\n
The Stephen Buttrum Brain Tumour Research Fellowship.<\/h3>\n