{"id":4772,"date":"2011-04-21T15:31:55","date_gmt":"2011-04-21T19:31:55","guid":{"rendered":"https:\/\/www.braintumour.ca\/research_recipients\/dr-alan-nichol-research-grant-2011\/"},"modified":"2020-05-20T19:07:59","modified_gmt":"2020-05-20T23:07:59","slug":"dr-alan-nichol-research-grant-2011","status":"publish","type":"research_recipients","link":"https:\/\/www.braintumour.ca\/fr\/laureats_de_la_recherche\/dr-alan-nichol-research-grant-2011\/","title":{"rendered":"Dr. Alan Nichol &#8211; Subvention de recherche 2011"},"content":{"rendered":"<p>Dr. Alan Nichol, Radiation Oncologist, BC Cancer, Vancouver, BC<\/p>\n<h5>Project Title: \u00ab\u00a0A Phase II study using 18F-FDOPA positron emission tomography for planning of neurosurgery and assessment of resection for high-grade gliomas\u00a0\u00bb<\/h5>\n<h3 class=\"underlined\">Research Summary:<\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-2263\" src=\"https:\/\/braintumour.ca\/wp-content\/uploads\/2019\/11\/Portrait-Big-Smile.jpg-nichol-e1573590762515-273x300.jpg\" alt=\"Dr. Alan Nichol\" width=\"273\" height=\"300\" srcset=\"https:\/\/www.braintumour.ca\/wp-content\/uploads\/2019\/11\/Portrait-Big-Smile.jpg-nichol-e1573590762515-273x300.jpg 273w, https:\/\/www.braintumour.ca\/wp-content\/uploads\/2019\/11\/Portrait-Big-Smile.jpg-nichol-e1573590762515-932x1024.jpg 932w, https:\/\/www.braintumour.ca\/wp-content\/uploads\/2019\/11\/Portrait-Big-Smile.jpg-nichol-e1573590762515-768x844.jpg 768w, https:\/\/www.braintumour.ca\/wp-content\/uploads\/2019\/11\/Portrait-Big-Smile.jpg-nichol-e1573590762515-1398x1536.jpg 1398w, https:\/\/www.braintumour.ca\/wp-content\/uploads\/2019\/11\/Portrait-Big-Smile.jpg-nichol-e1573590762515-640x703.jpg 640w, https:\/\/www.braintumour.ca\/wp-content\/uploads\/2019\/11\/Portrait-Big-Smile.jpg-nichol-e1573590762515-1024x1125.jpg 1024w, https:\/\/www.braintumour.ca\/wp-content\/uploads\/2019\/11\/Portrait-Big-Smile.jpg-nichol-e1573590762515-1200x1318.jpg 1200w, https:\/\/www.braintumour.ca\/wp-content\/uploads\/2019\/11\/Portrait-Big-Smile.jpg-nichol-e1573590762515-1311x1440.jpg 1311w, https:\/\/www.braintumour.ca\/wp-content\/uploads\/2019\/11\/Portrait-Big-Smile.jpg-nichol-e1573590762515-983x1080.jpg 983w, https:\/\/www.braintumour.ca\/wp-content\/uploads\/2019\/11\/Portrait-Big-Smile.jpg-nichol-e1573590762515.jpg 1500w\" sizes=\"auto, (max-width: 639px) 98vw, (max-width: 1199px) 64vw, 273px\" \/>Neurosurgeons use computed tomography (CT) and magnetic resonance imaging (MRI) to plan surgery for malignant brain tumours. These high-grade gliomas enhance when intravenous contrast is given for brain imaging. The aim of contemporary neurosurgery is to remove as much of the enhancing tumour as possible without causing disability for patients. However, outside the enhancing area, in parts of the brain that appear merely swollen on CT and MRI, there are also tumour cells.<\/p>\n<p>The 18F-FDOPA positron emission tomography (PET) tracer is an amino-acid analogue that is taken up by tumour cells. It can be injected intravenously and imaged with a PET scanner to find additional tumour cells in the parts of the brain that appear swollen. In this study, neurosurgeons will be provided with both MRI and 18F-FDOPA PET imaging for surgical planning. The extent of surgical resection will be studied by repeating the MRI and 18F-FDOPA PET imaging within a few days of surgery. It is hoped that use of the 18F-FDOPA PET imaging will facilitate better tumour resections and lead to better survival for patients.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dr. Alan Nichol, BC Cancer. Project: \u00ab\u00a0A Phase II study using 18F-FDOPA positron emission tomography for planning of neurosurgery and assessment of resection for high-grade gliomas\u00a0\u00bb<\/p>\n","protected":false},"featured_media":2264,"menu_order":0,"template":"","research_recipient_type":[285],"class_list":["post-4772","research_recipients","type-research_recipients","status-publish","has-post-thumbnail","hentry","research_recipient_type-grant-fr"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.0 (Yoast SEO v27.0) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Dr. Alan Nichol - Subvention de recherche 2011 - Fondation canadienne des tumeurs c\u00e9r\u00e9brales<\/title>\n<meta name=\"description\" content=\"Dr. Alan Nichol, BC Cancer. 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