Generously funded by Donors of Brain Tumour Foundation of Canada

David Shultz – Princess Margaret Cancer Centre

Project Title: “Factors Associated with Quality of Life and Neurocognitive Function in Patients with Brain Metastases: Analyses of a Prospective Longitudinal Study”

Description of Project:

Brain Metastases are a common complication of advanced cancer that can significantly impact a patients overall well-being and quality of life. In Canada, approximately 20,000 people are diagnosed with brain metastases each year. Patients with brain metastases experience distinct health challenges, which can exacerbate the impact of the range of physical and psychological symptoms commonly experienced by advanced cancer patients. Here we propose an analysis of data collected through our prospective study, where the quality of life and neurocognitive functioning is evaluated over time in patients with and without brain metastases. Through this study we aim to identify both the unique challenges faced by brain metastases patients and the clinical and treatment factors that most strongly contribute to declines in quality of life and neurocognitive functioning in this population. Ultimately, the research aims to facilitate the identification of brain metastases patients who may be at risk for declines in quality of life and neurocognitive functioning to permit early interventions, support and education for patients and families that are tailored to the needs of this population. This will facilitate development of targeted interventions that address the unique challenges of brain metastases patients to improve their outcomes.

What receiving this award means:

“This award will allow our research team to better understand how brain metastases affect our patients’ ability to live meaningful and productive lives. We have the opportunity to study in great detail the unique challenges faced our patients and the factors that most strongly contribute to their psychological and functional well-being.”