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Research will find the missing pieces of the puzzle. See the researchers we have funded.
This study will help my team understand the phenotypes of different types of quiescent (non-cycling) and cycling cells in various patient-derived GBM cell models and identify new targets for this disease.
Being awarded the DUNN with Cancer Brain Tumour Research Fellowship means that I can pursue high-impact research aimed at improving the quality of life for individuals facing glioblastoma, an aggressive and devastating brain cancer.
Being awarded the Brain Tumour Foundation of Canada Research Fellowship means the world to me at this pivotal stage of my academic and professional journey. It enables me to investigate a critical and underexplored aspect of pediatric brain tumour biology that could lead to more effective treatments for children.
Being awarded a Brain Tumour Research Studentship means opportunity. I am deeply honoured to be holding this award, and for this, I extend my deepest gratitude to the Taite Boomer Memorial Brain Tumour Foundation, enabling young researchers like me to strengthen the progression of research through the joint passion and generosity of this community
I am sincerely grateful to Brain Tumour Foundation of Canada and to the St. George Royal Canadian Legion whose generosity makes this experience possible. Their support empowers students to explore their potential and contribute meaningfully to the lives of patients and families.
Gliomas are the most common type of brain tumour in children, adolescents and young adults. An IDH mutation is a genetic change that can lead to glioma formation. IDH-mutant glioma is typically found in young adults, with these tumours universally progressing over time.
Glioblastoma (GBM) is a devastating brain tumour with limited treatment options. This project explores the role of the glymphatic system, the brain's waste removal and immune cell transport network, in GBM progression.
Although primary brain tumours vary widely in prognosis, people living with any brain tumour are at increased risk of cognitive deficits. These cognitive deficits can affect their ability to manage daily tasks, maintain social relationships, and continue to work or remain in school.
Meningioma is the most common primary brain tumour in adults. Although a large percentage are classified as benign, the more aggressive types of meningioma impose a significant morbidity and mortality burden on patients.
The current treatments for brain cancer do not work well and cause a lot of side-effects. This highlights the need to develop better treatments. There are several types of brain tumors. They differ in their age of onset, aggressiveness, and localization within the brain.
Attending school not only allows students to learn but the opportunity to develop interests, connect with peers, and form lifelong bonds. With your generous support we will explore pediatric brain tumour survivors' and their families' experience re-entering the education system after a cancer diagnosis.
Through their remarkable generosity, the Brain Tumour Foundation of Canada has enabled our interdisciplinary research group to develop artificial intelligence technologies to help discover new therapies against recurrent glioblastoma.
We hope this research will lead to the initiation of new clinical trials to optimize and expand the subset of patients with brain metastases who will derive the greatest clinical benefit from this therapy.
This research project, which has been 10 years in the making, is progressing very well, and will continue to do so thanks to this generous grant. Rest assured that we will continue to work tirelessly to improve the care of brain tumour patients.
I am thrilled and grateful to receive The Brain Tumour Foundation of Canada Mackenzie Rigg Brain Tumour Research Grant. These funds will launch an ambitious project in a completely new area of glioblastoma research, studying how age-related changes in the blood system fuel tumour growth.
In reading Allison's story, we see reflected many of our own patients and our own experiences as parents, daughters, partners, surgeons and researchers. This is a horrible cancer that robs families of time and memories.
I am grateful to the Brain Tumour Foundation of Canada and DUNN with Cancer for funding our Elevation Research Grant. This award provides vital resources to help our team advance research on novel biomarkers for high-grade gliomas.
Thank you to the BTFC and Taite Boomer Foundation for their endearing dedication and incredible support they provide to patients and brain cancer research. None of our work would be possible without this community’s generosity.
Being awarded a Brain Tumour Research Studentship means potential, opportunity, and impact. Receiving this award from the BTFC is an incredible honour, and I am deeply grateful to the generous donors for funding this opportunity.
Being awarded a Brain Tumour Research Studentship means the chance to pursue potentially lifesaving research. I have been searching for an area of study in which to pursue my own intellectual curiosity and also the potential to positively impact patient outcomes.
Being honored with the 2023 Brain Tumor Foundation of Canada Research Grant is a pivotal step for my nascent lab, propelling a high-risk, high-reward project. This grant not only provides essential funding but also validates the innovative potential of our work.
This award from the Brain Tumour Foundation of Canada is a tremendous honour for myself and my laboratory, where it allows us to spearhead important translational work in very high-risk medulloblastoma that we hope can one day benefit patients and their families.
The BTFC funding will allow us to start applying the most innovative machine learning methods to ensure patients with brain tumours in Ontario – including children – receive the highest quality radiotherapy possible.
I would like to thank the Brain Tumour Foundation of Canada for supporting this important work. Our project represents a novel collaboration between experts in translational medicine, clinical epidemiology, and neuro-oncology survivorship.
This award will allow our research team to better understand how brain metastases affect our patients’ ability to live meaningful and productive lives. We have the opportunity to study in great detail the unique challenges faced our patients and the factors that most strongly contribute to their psychological and functional well-being.
Thanks to the generous funding provided by the Brain Tumour Foundation of Canada and DUNN with Cancer, we are now poised to advance our research and delve deeper into elucidating key epigenetic factors that drive the progression of GBM and its resistance to therapies.
We are so grateful to the BTFC and DUNN with Cancer for the many levels of support they provide to the brain cancer research community. BTFC supports new ideas, innovation and transformative thinking about incredibly challenging problems like how to develop new treatments for a highly treatment-resistant brain tumour such as GBM.
Receiving the prestigious DUNN with Cancer Brain Tumour Research Fellowship is an exceptional honor and a pivotal moment in my academic and professional journey. This fellowship provides a remarkable opportunity to delve into the complexities of glioblastoma (GBM), a highly challenging and invasive form of brain cancer.
I am honoured to be awarded the William Donald Nash Brain Tumour Research Fellowship. Receiving this award will allow me to identify novel immunotherapy targets for childhood medulloblastoma utilizing cutting edge mass spectrometry techniques.
Being awarded a Brain Tumour Research Studentship means gives me the opportunity to do impactful patient-centered science at the Singh Laboratory. During my time here, I will explore the field of cancer biology in the context of brain tumours, specifically Glioblastoma.
This funding has enabled us to continue the promising research on targeting pannexin channels to stop communication between cells and reduce the growth and spread of glioblastoma tumours. Thanks to this funding we can support the technicians, graduate students, and expensive supplies we need to use in the lab to carry out this research.
On behalf of my collaborating investigators and myself, I would like to express immense gratitude to all of you for supporting our research that we know will have profound impact on the practice and delivery of care for pediatric brain tumour patients across Canada.
Cancer treatment has undergone many advancements in the past decade to improve patient quality of life and to provide new and improved treatment strategies. However, there is still a lot of work to be done, with current treatment strategies succumbing to resistance, and other more rare cancers remaining undruggable.
Glioblastoma (a fast-growing brain cancer) is the most common malignant brain tumor in adults. As a devastating diagnosis with a high mortality rate and rapid loss of function and independence, it is imperative to consider factors such as symptom management, maintaining independence and preserving or improving quality of life for the duration of the patients’ life.
This funding will allow us to dissect exciting data that has the potential to change the way that we are approaching treatment for one of the most aggressive forms of brain tumour, glioblastoma. We will focus not on the cancer cells themselves, which have eluted all treatment to date, but rather we will turn our focus to the supporting cells around the tumour.
This generous award from the Brain Tumour Foundation of Canada will support an innovative therapeutic development program underway in the Faculty of Health Sciences at McMaster University. In partnership with Prof. Sheila Singh and her team, we working to develop a new class of cancer therapies that can intercept and prevent the metastasis of cancers to the brain from other primary sites.
Radiosurgery is one of the common treatment options for patients with brain metastases. It has several benefits over other treatment options including reduced side effects, it’s non-invasive nature and improved quality of life especially when administered early.
The funds received from the Brain Tumour Foundation of Canada will allow us to build on exciting preliminary results and are critical to sustaining longer term studies aimed at evaluating clinical utility in childhood brain cancers.
Muhammadvaseem Shaikh Postdoctoral Research Fellow at McMaster University, Hamilton, ON Project Entitled: “Allogeneic, “off-the shelf” CD133 CAR-T immunotherapy for Glioblastoma” […]
Sami Alrashed – Medical Student, University of Windsor Supervisor: Dr. Lisa Porter Project: “Uncovering activation and plasticity of tumour microenvironment […]
As someone who has been directly affected by brain tumours, it is my greatest honour to be awarded the Brain Tumour Research Studentship.
Leandra Desjardins / Marco Bonanno – Sainte-Justine Children’s Hospital Project Title: “Targeted transition readiness workshops for pediatric brain tumour survivors: […]
Cynthia Hawkins – Hospital for Sick Children Project Title: “Investigating treatment targets in the DIPG immune landscape using single cell technology” […]
Xian Wang Postdoctoral Research Fellow at the Hospital for Sick Children, Toronto, ON Project Entitled: “Targeted mechanical ablation of Glioblastoma […]
Funded through the generosity of donors Chantel Cacciotti – London Health Sciences Centre- Children’s Hospital – London, ON Project Title: “Pediatric […]
Generously funded by Lori Stauber Daniel Schramek – Lunenfeld-Tanenbaum Research Institute – Toronto, ON Project Title: “Elucidating the genes that trigger […]
Funded through the generosity of donors Mary Jane Lim-Fat – Sunnybrook Health Sciences Centre – Toronto, ON Project Title: “Assessing molecular, […]
Generously Funded by the DUNN with Cancer Research Fund Andrew Beharry – University of Toronto, Mississauga, ON Project Title: “Predicting Temozolomide […]
Generously funded by an anonymous research fund Rolando Del Maestro – Neurosurgical Simulation and Artificial Intelligence Learning Centre, McGill University Montreal, […]
Generously funded by an anonymous research fund Alan Nichol – BC Cancer Project Title: “The Relationship between Magnetic Resonance Imaging White […]
Adrian Levine Resident Physician, Neuropathology, University of British Columbia, Vancouver General Hospital Project Entitled: “Improving Precision Medicine for Pediatriac Glioma” […]
Aiyireti (Dina) Dilinaer Undergraduate Science Student, University of Windsor Supervisor: Dr. John Trant Project: “Self-Immolative NanoCapsule – A New Form […]
Yujin Suk Medical Student, McMaster University Supervisor: Dr. Sheila Singh Project: “Identification of ITGA5 as a novel immunotherapeutic target against […]
Leonaes Brahel Tatchinda Kuete Undergraduate Science Student, McGill University Supervisor: Dr. Leandra Desjardins Project: “Understanding Social Behaviors in Pediatric Brain […]
Project Title: “Targeting Glioblastoma Recurrence with anti-ROBO1 Immunotherapy”
Project Title: “Mapping of Essential Amino Acid Metabolism for the Detection of Glioblastoma Multiforme Spread in Post-Surgical Patients”
David Fortin - Universite de Sherbrooke - Project Title: “Radioisotope Embedded in GlioTrap for Glioblastoma Treatment”.
Project Title: “Development of deep learning approaches for deciphering and targeting intra-tumoural heterogeneity in Glioblastoma”
Project title: “A universal drug delivery vehicle to transport drugs across the blood-brain barrier to target Glioblastoma”
2020 William Donald Nash Brain Tumour Research Fellowship Recipient Nicholas Mikolajewicz Postdoctoral Researcher Terrence Donnelly Centre for Cellular & Biomolecular Research University […]
Arun Parmar is entering his fourth year of Health Sciences at McMaster University. What does receiving this award mean to […]
Peter Liu is a second-year Medical Sciences student at Western University in London, Ontario. What are you studying/specializing in? I […]
Dr. Sara Elkashef, University Health Network. Project Title: "Radiation-immunotherapy combination treatment for glioblastoma: improving the therapeutic ratio"
Janet Ellis, University of Toronto. Project Title: “Evaluating the Impact of Dignity Therapy on Quality of Life in Patients with Brain Tumour: A Pilot Study”
Derek Tsang and Fiona Schulte, Princess Margaret Cancer Centre. Project Title: “Prospective Quality-of-Life Study of Children Treated with Repeat Radiotherapy for Brain Tumours (QoL-ReRT)”
Raymond Reilly, University of Toronto. Project Title: “Radiation Nanomedicine for Intraoperative Treatment of Glioblastoma Multiforme (GBM)”
Shane Harding, Princess Margaret Cancer Centre. Project Title: “Radiotherapy-induced brain toxicity: A mechanistic basis and therapeutic opportunity”
Mehul Gupta is an Undergraduate Science Student at the University of Calgary. Project title: “The Perfect Shot: Generation of Personalized Vaccines for Refractory Childhood Brain Tumours”
Dr. Brent Guppy, William Donald Nash Brain Tumour Research Fellow, University of Manitoba. Project Title: "Enhancing selumetinib-mediated killing of SHH medulloblastoma"
Pejman Jabehdar Maralani, Sunnybrook Health Sciences Centre. Project Title: “Advanced magnetic resonance imaging for detection of tumour regions enriched with glioma stem cell niches”
Qi Zhang, London Health Sciences Centre. Project Title: “Discovering Lung Cancer Biomarkers Predictive of Brain Metastasis”
Di Zhu is an Undergraduate Science Student at the University of Toronto. Project title: "Targeting Obligate Pathways of Metastasis and Recurrence in Medulloblastoma”
Sabra Salim is an Undergraduate Science Student at McMaster University. Project title: "Improving the safety of CAR-T cells using inducible caspase-9 safety switch”
Quin Xie is an Undergraduate Science Student at the University of Toronto. Project title: "Automated histopathologic classification of brain tumours”
Dr. Ugljesa Djuric, Richard Motyka Brain Tumour Research Fellow, University Health Network. Project Title: "Systematic proteomic profiling and subclassification of Glioblastoma”
Dr. Vijay Ramaswamy, Hospital for Sick Children. Projec: "Mechanisms of treatment resistance in supratentorial ependymoma"
Tommy Alain, Children’s Hospital of Eastern Ontario Research Institute (CHEO RI). Project: "Characterization of a New Pharmaco-Viral Approach for the Treatment of Brain Cancer"
Thomas Klonisch, University of Manitoba. Project: "Novel minimally-invasive immune-proteome biomarker strategy for Glioblastoma"
Phedias Diamandis, University Health Network / Princess Margaret Cancer Centre. Project: "The brAIn Project: biological rendering through Artificial Intelligence and neural networks"
Gelareh Zadeh, Princess Margaret Cancer Center. Project: “Pimonidazole as a specific marker for hypoxia in glioblastoma and identification of marker genes associated with its uptake”
Oleksandra Kaskun is an Undergraduate Science Student at University of Toronto. Project title: "Targeting Bevacizumb resistance via LIVE-mediated vascular mimicry in Glioblastoma"
David Bobrowski is an Undergraduate Science Student at McMaster University. Project: "Co-expression of EphA2 &A3 Receptor Tyrosine Kinases Mark Brain Tumour Initiating Cell Population in Recurrent Human Glioblastoma”
Tae Hoon Lee is a Medical Student at University of British Columbia. Project: ”Proteomic profiling of low grade gliomas using a novel platform of mass spectrometry on formalin fixed paraffin embedded brain tumour tissue specimens”
Ashley Adile is an Undergraduate Science Student at McMaster University. Project:"Small molecule inhibitors targeting self-renewal as a therapeutic option for recurrent childhood medulloblastoma"
Alexander Rodzinka is an Undergraduate Science Student at University of Windsor. Project: "Targeting Unique Aspects of Cell Cycle Signalling as Therapeutic Direction for Glioblastoma Multiforme"
Carolina Nor, William Donald Nash Brain Tumour Research Fellow, Hospital for Sick Children, Toronto, ON. Project Title: "Rationale targeting of very high risk medulloblastoma of childhood"
Karl Narvacan is a Medical Student at the University of Alberta. Project: “Evaluation of nCounter technology in copy number variation analysis for the integrated classification and predictive prognosis of diffuse gliomas”
Matthew Dankner is a Medical Student at McGill University. Project: "Using patient-derived xenograft models to identify mediators of brain metastasis in diverse cancers"
Colin Maslink is a Medical Student at the University of Toronto. Project: "Targeted therapeutic disruption of the blood-brain barrier in childhood brainstem cancers"
Dr. Matias Mariani, Health Sciences North/Horizon Sante-Nord. Project: "Teleneuropsychology: Assessment and Intervention in High-Grade Primary Brain Tumours"
Dr. Paula Foster, University of Western Ontario. Project: "Investigating the impact of radiation-induced damage on promoting metastatic tumour growth in the brain"
Lisa Porter, Associate Professor, Biological Sciences, University of Windsor. Project Title: "Optimizing Novel Therapies for Medulloblastoma"
Steven Selchen, Sunnybrook Research Institute. Project: "A Mindfulness-Based Intervention to Improve Quality of Life Among Brain Tumour Survivors"
Sébastien Perreault, CHU Sainte-Justine. Project: "Steady-state visual evoked potentials to assess visual function in children with optic pathway glioma: a new approach"
Andrea Lo, Nazira Mamdani Brain Tumour Research Fellow. Project Title: Treatment approaches, outcomes and complications in adolescents and young adults of intracranial germ cell tumours
Bayan Aloran is a student at the University of Windsor. Project: “Evaluation of anticancer activities of alcoholic extract of long pepper in human neuroblastoma and glioblastoma cells”
Alexandre Corriveau is a student at the Universite de Moncton. Project: "Investigating non-coding RNA’s underlying temozolomide resistance in glioblastoma multiforme"
Omid Shearkhani is a student at the University of Toronto. Project: "Developing and evaluating the performance of an automated computer-aided detection software for the follow-up of metastatic brain tumours"
Faran Rashid is a student at the University of Northern British Columbia. Project: “Searching for Potential New Anti-Cancer Compound(s) Against Human Glioblastoma Cancer Cells from British Columbia Wild Mushrooms”
Daniel Huang is a student at McGill University. Project: “Understanding Top1 biology in the treatment of malignant brain tumours”
Dr. Michael Taylor; Hospital for Sick Children. Project: "Unraveling intratumor heterogeneity in childhood medulloblastoma"
Sheila Singh, McMaster University. Project: "Therapeutic targeting of Sox2+ treatment-refractory stem cells in sonic hedgehog-dependent pediatric medulloblastoma"
Dr. Pejman Jabehdar Maralani; University of Toronto. Project: "Quantitative blood oxygenation level dependent (qBOLD) MR imaging of glioblastoma multiforme for assessment of tumour hypoxia"
Dr. Ian Lorimer; Ottawa Hospital Research Institute. Project: "Targeting Glioblastoma tumour initiating cells via inhibition of fatty acid synthase"
Dr. John Kelly; University of Calgary. Project: "Combinatorial treatment of glioblastoma initiating cells with microglial cytokines and STAT3 inhibition"
Florence Cavalli, Stephen Buttrum Brain Tumour Research Fellow. Project Title: Deciphering the transcriptional regulation underlying Medulloblastoma subgroups.
Cathy Lee, Richard Motyka Brain Tumour Research Fellow. Project Title: Myc- mediated cell extrinsic signaling in brain tumour progression
Thusyanth is a biomedical sciences student at McMaster University. Project "Sox2 marks the treatment-refractory population on Shh-dependent medulloblastoma stem cells".
Samer is a biology student at the University of Windsor. Project: Role of Spy1 in Neurogenesis; Implications in the Development of High Grade Glioma
Shriya Deshmukh is a neuroscience student at the University of Toronto. Project: "Novel clinical applications of THOR methylation in cancer"
Nadia is a first-year medical student at Western University in London, ON. Project title: Vision-Related Quality of Life in Patients with Pituitary Tumours
Dr. Mark Ruschin, Sunnybrook Odette Cancer Centre. Project: Comparison of healthy tissue sparing using different radiation delivery devices for focal irradiation of multiple brain metastases
Dr. Kevin Petrecca, Montreal Neurological Institute and Hospital. Project: "Development of novel therapeutics to prevent brain cancer invasion"
Dr. Aru Narendran, University of Calgary. Project: "A Virus to Kill by: Double-deleted Vaccinia virus (VVdd) as a novel therapeutic agent for a defiant pediatric brain tumour".
Dr. Sabine Mai, Manitoba Institute of Cell Biology. Project: "Characterization of ependymomas into favourable and non-favourable groups based on their 3D nuclear telomere profiles."
Dr. Slawomir Kumala, William Donald Nash Brain Tumour Research Fellowship. Project Title: Combi-molecule, ZRBA1, as a novel molecular targeted therapy integrated with high dose rate ionizing radiation to treat malignant glioma tumours
Julie Poitras is a BSc Biochemistry student at the Université de Moncton. Project: "Understanding temozolomide resistance in glioblastomas using a metabolomics-based approach"
Robyn Leah McClelland is in the medicine program at the University of Manitoba. Project: "Investigating the role of selective pathway antagonists in highly self-renewing and invasive medulloblastoma subpopulations"
Branavan Manoranjan is a Medicine and Biochemistry/Biomedical Sciences student at McMaster University. Project: "The role of Wnt signaling in human medulloblastoma brain tumour-initiating cells"
Santo Spencer Briguglio is a Biochemistry and Biotechnology student at the University of Windsor. Project: "The Efficacy of Cdk Inhibitors as a Novel Therapeutic Approach for Medulloblastoma"
Rajas Tipnis is in the BSC Honours program in Biological Sciences at the University of Manitoba. Project: "Inhibition of the DNA single strand break repair pathway in the treatment of malignant brain tumours"
Dr. Ash Singhal, University of British Columbia. Project: "Targeting the Elimination of Brain Tumour Initiating Cells by disrupting the P13K pathways"
Thanh Binh Nguyen, Ottawa Hospital. Project: "Diagnostic Accuracy of Perfusion and Diffusion MRI in Patients with Suspected Recurrent High Grade Gliomas"
Thierry M. Muanza, Jewish General Hospital Segal Cancer Centre. Project: "Novel DNA damaging and anti-EGFR combi-molecule, ZR2003, to potentiate ionizing radiation in malignant glioma models"
Matthew Hebb, Western University, London, Ontario. Project Title: "HSP27 as a New Molecular Target in Glioblastoma"
Karen Goddard, BC Cancer. Project: Feasibility Study: "Cerebrovascular disease and Late Effects in Survivors of Craniopharyngioma"
Spencer Gibson, University of Manitoba. Project: "Targeting Bci-2 family members for treatment under hypoxia in glioblastoma multiforme tumours"
Paula Foster, Robarts Research Institute. Project: "In Vivo MRI Characterization of Changing Blood-Tumour Barrier Permeability in a Mouse Model of Brain Metastasis"
Dr. David Fortin, Universite de Sherbrooke. Project: "Characterization of the chemoresistance profiles of malignant gliomas - A step towards individualized treatments"
Dr. Gelarah Zadeh, University of Toronto. Project: "Identifying Molecular Therapeutic Targets for Bone invasive Meningiomas"
Dr. James Rutka, Hospital for Sick Children. Project: "The role of dysregulated HGF/c-Met pathway signalling in medulloblastomas dissemination"
Dr. Paula de Robles, a Clinical Assistant Professor, University of Calgary in Calgary, Alberta, Research Project into glioblastoma
Dr. Tamra Ogilvie, University of Manitoba. Project: "Comparing the stem cell properties of the most invasive and non-invasive malignant brain tumour cells."
Dr. Alan Nichol, BC Cancer. Project: "A Phase II study using 18F-FDOPA positron emission tomography for planning of neurosurgery and assessment of resection for high-grade gliomas"
Dr. Pier Jr Morin, University of Moncton. Project Title: "Understanding the Impact of tribbles proteins on glioblastoma development"
Dr. Jean-Claude Bertrand, Royal Victoria Hospital/McGill University. Project: "Brain penetrability and in vivo potency of novel multi-targeted combi-drugs"
Dr. Abhijit Guha, The Hospital for Sick Children (Sick Kids). Project: "The Aberrant Role of Peroxisomes in Malignant Glioma"
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